DESCRIPTION
Clear colorless solution.
PHARMACOLOGICAL CHARACTERISTICS
Calcium chloride activates the reticuloendothelial system and phagocytic function of leukocytes, increases the tone of the sympathetic innervation, increases excretion of adrenaline activates the synthesis of enzymes. Calcium ions are necessary for work of skeletal muscles and myocardium, formation of bone tissue, sealing the walls of blood vessels, have antiinflammatory effect, prevent development of edema. These ions are present in the process of hemocoagulation, contribute to the transformation of prothrombin to thrombin.
APPLICATION
Solution of calcium chloride 10% for injection is used as an anti-inflammatory agent for treatment of animals with pneumonia, pleurisy, peritonitis, toxic liver damage, parenchymatous hepatitis, nephritis, radiation sickness, toxic pulmonary edema, hypertension and pulmonary edema, laryngeal edema, edema disease of pigs, as a hemostatic agent in case of nasal, gastrointestinal, lung, uterine and postoperative bleedings. As desensitizing agent in case of allergic diseases (asthma, serum sickness, itchy skin disease, scarlatina of horses, chronic urticaria of horses and cattle) and allergic complications after the use of medicines. As soothing, normalizing the nervous system product during vegetative neurosis, eclampsia of dogs, false milk fever, paralytic myoglobinuria of horses. In obstetric practice (in case of endometritis, metritis, for stimulation of paturation, accelerating separation of animals heam, prevention of abortion, in case of maternity paresis, postpartum hematuria of cows). Apply with hypotonia and atony of cattle proventriculus, hemorrhagic gastroenteritis, tetany of young animals, for improvement of calcium level in blood, withdrawal of seizures, assign as an antidote for poisoning by magnesium salts, oxalic acid, soluble salts of fluorine and oxalic acids.
DOSAGE
The drug is injected only slowly intravenously!
Slowly at doses (ml per animal):
cattle – 150-400;
horses – 100-300;
sheep, goats – 10-30;
pigs – 10-20,
dogs – 5-15.
Before the injection the drug is heated to body temperature of the animal. Apply 1 time per day. If necessary, repeat the treatment after 24-48 hours.
CONTRAINDICATIONS
Do not apply to animals with tendency to thrombosis, high level of calcium blood. Do not apply subcutaneously or intramuscularly, causing severe irritation and tissue necrosis.
SIDE EFFECTS
Sometimes is possible slowdown of animals rate that passes quickly and independently.
PRECAUTIONS
Before the injection of the drug must be heated to body temperature of the animal. The drug is injected slowly, making sure the syringe needle is in the lumen of the vein. In case of rapid injection may occur ventricular fibrillation of the heart. If in case of injection part of the drug got subcutaneously, it is necessary to inject a large amount of isotonic solution sodium chloride 0.9% around the place of injection for preventation of tissue necrosis. The drug has antagonistic action to drugs magnesium, reacts with oxalic acid and its salts, fluoride acid forming toxic compounds.
STORAGE
Dry, dark place at temperature from 0 to 25°C.
Expiration date in ampoules – 10 years, in bottles – 3 years.
СOMPOSITION
100 ml containing active substances (g): calcium chloride crystal – 10.0.
PACKAGING
Solution in glass bottles 200 ml.