{"id":401,"date":"2017-08-01T13:28:32","date_gmt":"2017-08-01T10:28:32","guid":{"rendered":"https:\/\/agroolkar.com.ua\/?post_type=production&p=401"},"modified":"2021-04-09T15:22:38","modified_gmt":"2021-04-09T12:22:38","slug":"profiverm-1-o-l-kar-inektsionnyj","status":"publish","type":"production","link":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/","title":{"rendered":"Profiverm 1% O.L.KAR. for injection"},"content":{"rendered":"

\u0421<\/strong>OMPOSITION<\/strong><\/p>\n

1 ml contains active substances:<\/p>\n

ivermectin \u2013 10 mg;<\/p>\n

excipients \u2013 up to 1 ml<\/p>\n

 <\/p>\n

PACKAGING<\/strong><\/p>\n

Ampoules of brown glass of 1, 2 and 5 ml placed in cardboard boxes and bottles of brown glass, closed with a rubber stopper under an aluminum cap of 10, 20, 50, 100 and 200 ml.<\/p>\n

 <\/p>\n

DESCRIPTION.<\/strong>\u00a0Homogeneous, clear colourless to pale yellow, slightly viscous, sterile non-aqueous solution.<\/p>\n

PHARMACOLOGICAL CHARACTERISTICS<\/strong>. Ivermectin is a 22,23-dihydro derivative of an avermectin (which is a fermentation product produced by\u00a0Streptomyces avermitilis<\/em>) and consists of 2 homologues: B1a and B1b.\u00a0 It is a parasiticide with nematocidal, insecticidal and acaricidal activity documented in a wide range of domesticated animals.<\/p>\n

Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action.\u00a0 Compounds of this class bind selectively and with high affinity to glutamate gated chloride ion channels which occur in invertebrate nerve and muscle cells.\u00a0 This leads to an increase in the permeability of the cell membrane to chloride ions with the hyper-polarisation of the nerve or muscle cell resulting in paralysis and death of the parasite.<\/p>\n

After subcutaneous administration the drug has the highest capacity for absorption. Ivermectin is metabolized in the liver by oxidation processes, secreted mainly in the feces. Less than 5% of the drug is excreted in the urine.<\/p>\n

APPLICATION<\/strong>. For the treatment and control of the following species of gastrointestinal roundworms, lungworms, eyeworms, warbles, mites and sucking lice in cattle, sheep, goats, pigs, dogs caused by:<\/p>\n

cattle: gastrointestinal nematodes \u2013 Ostertagia ostertagi, O. lyrata, Trichostrongylus axei, Trichostrongylus columbriformis, Haemonchus placei (including third stage larvae), Nematodirus spp. (mature forms); pulmonary nematodes \u2013 Dictyocaulus viviparus (adults and fourth larvae stage); itch tick \u2013 Sarcoptes bovis, Psoroptes bovis; gadfly (in larvae phase) \u2013 Hypoderma lineatum, H. bovis; lice \u2013 Linognathus vituli, Haematopinus eurysternus, Solenopoles capillatus; louse \u2013 Bovicola bovis;<\/p>\n

sheep and goats: gastrointestinal nematodes \u2013 Haemonchus contortus, (mature and the third and fourth larvae stage), Trichostrongylus vitrinus (mature forms), T. columbriformis (mature and fourth stage larvae), Nematodirus filicollis (mature and fourth stage larvae), Oesophagostomum colombianum, O. venulosum (mature forms), Charbetia ovina (mature forms), Trichuris ovis (mature forms); pulmonary nematodes \u2013 Dictyocaulus filaria (mature and fourth stage larvae), Protostronlylus spp. (mature forms); itch tick \u2013 Sarcoptes scabiei, Psoroptes communis (var. Ovis); nasopharyngeal gadflies \u2013 Oestrus ovis (all larval stages);<\/p>\n

pigs: gastrointestinal nematodes \u2013 Ascaris suum, Hyostrongylus rubidus (mature and fourth stage larvae), Oesophagostomum spp., Strongyloides ransomi (mature forms); pulmonary nematodes \u2013 Metastrongylus spp. (mature forms); lice \u2013 Haematopinus suis; itch tick \u2013 Sarcoptes suis.<\/p>\n

dogs: nematodes \u2013 Dirofilaria immitis, D. repens, Toxascaris leonine, Toxocara canis, Uncinaria stenocephala, Ancylostoma caninum; ticks \u2013 Sarcoptes canis, Demodex canis, Otodectes cynotis; lice \u2013 Linognathus setosus.<\/p>\n

DOSAGE.<\/strong>\u00a0The drug is used once only subcutaneously at doses:<\/p>\n

cattle, sheep and goats: 1 ml per 50 kg of body weight (0.2 mg ivermectin per 1 kg of body weight) injected into the area of the shoulder-blade;<\/p>\n

pigs: 1 ml per 33 kg of body weight (0.3 mg ivermectin per 1 kg of body weight) injected into the middle section of the neck;<\/p>\n

dogs: 0.1-0.2 ml per 5 kg of body weight (0.2-0.4 mg ivermectin per 1 kg of body weight).<\/p>\n

CONTRAINDICATIONS<\/strong>. The product is for administration only by the subcutaneous route and must not be given via other routes.\u00a0 It should not be used in other species than those indicated as severe reactions, including fatalities in dogs, may occur.<\/p>\n

Do not use for dogs of breeds Collie, Bobtail and their hybrids, small breeds of dogs and puppies under 3 months. To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.<\/p>\n

PRECAUTIONS<\/strong>. Cattle must not be slaughtered for human consumption until 49 days after the last treatment.<\/p>\n

This product should not be used in cattle producing milk for human consumption.\u00a0 The product should not be used in non-lactating dairy cows including pregnant heifers within 60 days of calving.<\/p>\n

Sheep must not be slaughtered for human consumption until 42 days after the last treatment.<\/p>\n

This product should not be used in lactating ewes producing milk for human consumption.<\/p>\n

Pigs must not be slaughtered for human consumption until 28 days after the last treatment.<\/p>\n

STORAGE<\/strong>. Dry, dark place, away from children at the temperature from 5\u00b0C to 25\u00b0C.<\/p>\n

The drug is stored separately from food, beverages, including the animal feed.<\/p>\n

SHELF-LIFE<\/strong>\u00a0\u2013 3 years from the date of manufacture.<\/p>","protected":false},"featured_media":3894,"template":"","meta":{"_acf_changed":false},"product":[5,61,4,57,56,59,3,58,50],"class_list":["post-401","production","type-production","status-publish","has-post-thumbnail","hentry","product-antigelmintiki","product-verblyudi","product-veterinarni-preparati","product-vivtsi","product-kozi","product-korovi","product-produktsiya","product-svini","product-sobaki"],"acf":[],"yoast_head":"\nProfiverm 1% O.L.KAR. for injection - O.L.KAR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Profiverm 1% O.L.KAR. for injection - O.L.KAR\" \/>\n<meta property=\"og:description\" content=\"\u0421OMPOSITION 1 ml contains active substances: ivermectin \u2013 10 mg; excipients \u2013 up to 1 ml   PACKAGING Ampoules of brown glass of 1, 2 and 5 ml placed in cardboard boxes and bottles of brown glass, closed with a rubber stopper under an aluminum cap of 10, 20, 50, 100 and 200 ml.   […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/\" \/>\n<meta property=\"og:site_name\" content=\"O.L.KAR\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/agroolkar.com.ua\/\" \/>\n<meta property=\"article:modified_time\" content=\"2021-04-09T12:22:38+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"500\" \/>\n\t<meta property=\"og:image:height\" content=\"700\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/\",\"url\":\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/\",\"name\":\"Profiverm 1% O.L.KAR. for injection - O.L.KAR\",\"isPartOf\":{\"@id\":\"https:\/\/agroolkar.com.ua\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/agroolkar.com.ua\/production\/profiverm-1-o-l-kar-inektsionnyj\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg\",\"datePublished\":\"2017-08-01T10:28:32+00:00\",\"dateModified\":\"2021-04-09T12:22:38+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[[\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/\"]]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#primaryimage\",\"url\":\"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg\",\"contentUrl\":\"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg\",\"width\":500,\"height\":700},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430\",\"item\":\"https:\/\/agroolkar.com.ua\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"\u041f\u0440\u043e\u0444\u0456\u0432\u0435\u0440\u043c 1% O.L.KAR. \u0434\u043b\u044f \u0456\u043d’\u0454\u043a\u0446\u0456\u0439\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/agroolkar.com.ua\/en\/#website\",\"url\":\"https:\/\/agroolkar.com.ua\/en\/\",\"name\":\"O.L.KAR\",\"description\":\"\u0415\u0449\u0451 \u043e\u0434\u0438\u043d \u0441\u0430\u0439\u0442 \u043d\u0430 WordPress\",\"publisher\":{\"@id\":\"https:\/\/agroolkar.com.ua\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/agroolkar.com.ua\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/agroolkar.com.ua\/en\/#organization\",\"name\":\"O.L.KAR\",\"url\":\"https:\/\/agroolkar.com.ua\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/agroolkar.com.ua\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2025\/02\/unnamed.jpg\",\"contentUrl\":\"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2025\/02\/unnamed.jpg\",\"width\":160,\"height\":160,\"caption\":\"O.L.KAR\"},\"image\":{\"@id\":\"https:\/\/agroolkar.com.ua\/en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/agroolkar.com.ua\/\",\"https:\/\/www.instagram.com\/olkar_agrozoovet\/#\",\"https:\/\/www.youtube.com\/channel\/UCT1lLuXdgBejmFGWwHbi-UA\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Profiverm 1% O.L.KAR. for injection - O.L.KAR","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/","og_locale":"en_US","og_type":"article","og_title":"Profiverm 1% O.L.KAR. for injection - O.L.KAR","og_description":"\u0421OMPOSITION 1 ml contains active substances: ivermectin \u2013 10 mg; excipients \u2013 up to 1 ml   PACKAGING Ampoules of brown glass of 1, 2 and 5 ml placed in cardboard boxes and bottles of brown glass, closed with a rubber stopper under an aluminum cap of 10, 20, 50, 100 and 200 ml.   […]","og_url":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/","og_site_name":"O.L.KAR","article_publisher":"https:\/\/www.facebook.com\/agroolkar.com.ua\/","article_modified_time":"2021-04-09T12:22:38+00:00","og_image":[{"width":500,"height":700,"url":"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"8 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/","url":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/","name":"Profiverm 1% O.L.KAR. for injection - O.L.KAR","isPartOf":{"@id":"https:\/\/agroolkar.com.ua\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#primaryimage"},"image":{"@id":"https:\/\/agroolkar.com.ua\/production\/profiverm-1-o-l-kar-inektsionnyj\/#primaryimage"},"thumbnailUrl":"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg","datePublished":"2017-08-01T10:28:32+00:00","dateModified":"2021-04-09T12:22:38+00:00","breadcrumb":{"@id":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":[["https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/"]]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#primaryimage","url":"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg","contentUrl":"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2017\/08\/3399.jpg","width":500,"height":700},{"@type":"BreadcrumbList","@id":"https:\/\/agroolkar.com.ua\/en\/production\/profiverm-1-o-l-kar-inektsionnyj\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u0413\u043b\u0430\u0432\u043d\u0430\u044f \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0430","item":"https:\/\/agroolkar.com.ua\/en\/"},{"@type":"ListItem","position":2,"name":"\u041f\u0440\u043e\u0444\u0456\u0432\u0435\u0440\u043c 1% O.L.KAR. \u0434\u043b\u044f \u0456\u043d’\u0454\u043a\u0446\u0456\u0439"}]},{"@type":"WebSite","@id":"https:\/\/agroolkar.com.ua\/en\/#website","url":"https:\/\/agroolkar.com.ua\/en\/","name":"O.L.KAR","description":"\u0415\u0449\u0451 \u043e\u0434\u0438\u043d \u0441\u0430\u0439\u0442 \u043d\u0430 WordPress","publisher":{"@id":"https:\/\/agroolkar.com.ua\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/agroolkar.com.ua\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/agroolkar.com.ua\/en\/#organization","name":"O.L.KAR","url":"https:\/\/agroolkar.com.ua\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/agroolkar.com.ua\/en\/#\/schema\/logo\/image\/","url":"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2025\/02\/unnamed.jpg","contentUrl":"https:\/\/agroolkar.com.ua\/wp-content\/uploads\/2025\/02\/unnamed.jpg","width":160,"height":160,"caption":"O.L.KAR"},"image":{"@id":"https:\/\/agroolkar.com.ua\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/agroolkar.com.ua\/","https:\/\/www.instagram.com\/olkar_agrozoovet\/#","https:\/\/www.youtube.com\/channel\/UCT1lLuXdgBejmFGWwHbi-UA"]}]}},"_links":{"self":[{"href":"https:\/\/agroolkar.com.ua\/en\/wp-json\/wp\/v2\/production\/401","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/agroolkar.com.ua\/en\/wp-json\/wp\/v2\/production"}],"about":[{"href":"https:\/\/agroolkar.com.ua\/en\/wp-json\/wp\/v2\/types\/production"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/agroolkar.com.ua\/en\/wp-json\/wp\/v2\/media\/3894"}],"wp:attachment":[{"href":"https:\/\/agroolkar.com.ua\/en\/wp-json\/wp\/v2\/media?parent=401"}],"wp:term":[{"taxonomy":"product","embeddable":true,"href":"https:\/\/agroolkar.com.ua\/en\/wp-json\/wp\/v2\/product?post=401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}