{"id":375,"date":"2017-07-31T17:59:37","date_gmt":"2017-07-31T14:59:37","guid":{"rendered":"https:\/\/agroolkar.com.ua\/?post_type=production&p=375"},"modified":"2021-11-08T16:08:20","modified_gmt":"2021-11-08T13:08:20","slug":"klozan-inektsionnyj-evro","status":"publish","type":"production","link":"https:\/\/agroolkar.com.ua\/en\/production\/klozan-inektsionnyj-evro\/","title":{"rendered":"Closan 5% euro injection solution"},"content":{"rendered":"

\u0421OMPOSITION<\/strong><\/p>\n

1 ml contains: closantel \u2013 50 mg;<\/p>\n

 <\/p>\n

PACKAGING<\/strong><\/p>\n

Glass bottles of 10, 50, 100 and 250 ml.<\/p>\n

Bottles sealed with gray rubber stopper, with an aluminium cap on top<\/p>\n

 <\/p>\n

\u00a0<\/strong><\/p>\n

DESCRIPTION.\u00a0<\/strong>Clear thick yellow solution.<\/p>\n

PHARMACOLOGICAL CHARACTERISTICS.\u00a0ATCvet QP52A, anti-distomiasis, anti-nematodosis and anti-cestodiasis veterinary drugs (QP52AG09, clo\u00adsantel).<\/em><\/strong><\/p>\n

The active ingredient of the drug \u2013 closantel, antiparasitic agent, structurally derived salicylanilide that has a long ef\u00adfect on endo- and ectoparasites.<\/p>\n

Closantel blocks phosphorylation process (formation of ATP) in the body of parasites through interference in the process of transporting electrons, changing energy me\u00adtabolism, resulting in the death of parasites.<\/p>\n

Closantel has a wide range of actions, effective in the treatment of parasitic diseases of cattle and small rumi\u00adnants caused by nematodes, trematodes and arthropods.<\/p>\n

Closantel is rapidly absorbed after oral or intramuscular administration. Maximum concentration in the blood of sheep is reached after 8-24 hours after administration, the blood of cattle \u2013 24-48 hours. The half-decomposi\u00adtion is approximately 12-15 days.<\/p>\n

Most part \u00a0of used closantel is concentrated in the lungs and kid\u00adneys, and the main way of its metabolism is renewable deionization.<\/p>\n

APPLICATION.\u00a0<\/strong>Prevention and treatment of cattle and small ruminants from the following diseases:<\/p>\n

cattle:<\/strong><\/p>\n

– fasciolosis (Fasciola hepatica<\/em>, mature and late larval forms);<\/p>\n

– nematodosis (adult and larval forms\u00a0Bunostomum spp., Haemonchus \u0441ontortus, Haemonchus placei\u00a0<\/em>and\u00a0Oesophagostomum radiatum<\/em>);<\/p>\n

– hypodermosis caused by the larvae of subcutaneous gadfly\u00a0Hypoderma spp.;<\/em><\/p>\n

sheep, goats:<\/strong><\/p>\n

– fasciolosis (Fasciola hepatica<\/em>, mature and late larval forms);<\/p>\n

– nematodosis (adult and larval forms\u00a0Bunostomum spp., Haemonchus \u0441ontortus, Haemonchus placei\u00a0<\/em>and\u00a0Oesophagostomum radiatum, Chabertia ovina<\/em>);<\/p>\n

– oestrosis (Oestrosis ovis<\/em>).<\/p>\n

DOSAGE.\u00a0<\/strong>The drug should be given only by subcutaneous once at the doses given in the table. It is recom\u00admended to inject the \u00a0the dose volume \u00a0in few different spots.<\/p>\n

CONTRAINDICATIONS.\u00a0<\/strong>Do not use with other \u00a0antiparasitic chlorine-organic drugs. Do not use for dairy and pregnant cattle in the last trimester of pregnancy.<\/p>\n

PRECAUTIONS.\u00a0<\/strong>Slaughter of animals for meat is per\u00admitted in 28 days, using milk for human nutrition \u2013 14 days after the drug usage. Slight inflammation in the in\u00adjection site is possible, but it disappears independently in two \u2013 three days after injection.<\/p>\n

Some breeds of cattle (Charolais and its hybrids) are par\u00adticularly sensitive to the drug, approximately 2% of the animals had anaphylactic reactions after the injection.<\/p>\n

STORAGE.\u00a0<\/strong>Store in a cool, dry, dark place at the tem\u00adperature from 5 to 25\u00b0C.<\/p>\n

Expiration date \u2013 2 years\u00a0<\/strong>from the date of manufacture.<\/p>\n\n\n\n\n\n
\n

Type animals<\/strong><\/p>\n<\/td>\n

\n

Diseases<\/strong><\/p>\n<\/td>\n

\n

The dose by<\/strong><\/p>\n

the active substance<\/strong><\/p>\n<\/td>\n

\n

Dose<\/strong><\/p>\n<\/td>\n<\/tr>\n

Cattle<\/strong><\/td>\nfasciolosis<\/p>\n

nematodosis<\/p>\n

hypodermosis<\/td>\n

2,5 mg closantel per kg of body weight<\/p>\n

2,5 mg closantel per kg of body weight<\/p>\n

5 mg closantel per kg of body weight<\/td>\n

0,5 ml\/10 kg of body weight<\/p>\n

0,5 ml\/10 kg of body weight<\/p>\n

1 ml\/10 kg of body weight<\/td>\n<\/tr>\n

Sheep, goats<\/strong><\/td>\nfasciolosis<\/p>\n

nematodosis, oestrosis<\/td>\n

5 mg closantel per kg of body weight<\/p>\n

2,5 mg closantel per kg of body weight<\/td>\n

1 ml\/10 kg of body weight<\/p>\n

0,5 ml\/10 kg of body weight<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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