СOMPOSITION

1 ml contains active ingredients:

Oxyclozanide – 95 mg;

Pyrantel pamoate – 200 mg.

PACKAGING

The product is packed in glass or polypro­pylene bottles of 50 and 1000 ml

DESCRIPTION. Homogeneous emulsion of light yel­low color without the expressed smell and taste.

PHARMACOLOGICAL CHARACTERISTICS. The combination of two active drug substances – pyrantel pamoate and oxyclozanide – provides a wide range of anthelmintic activity against major pathogens of dis­tomiasis and nematodosis, parasites in cattle, sheep and goats.

Oxyclozanide – synthetic compound from the group of salicylanilide, specific action of it causes the disruption of the oxidative phosphorylation process in trematodes altering metabolic processrs of the parasites causing their death. Oxyclozanide is highly effective anthelmintic, active against larvae over two-month old and mature trematodes (Fasciola hepatica, Dicrocoelium lanceatum, Paramphistomum ichikawai, Liorchis scotiae).

Pyrantel pamoate – synthetic compound from the group of pyrimidine, which causes a specific depolar­ized neuromuscular blockade on nematodes, and due to paralysis of the muscles of worms, they are derived from the gut peristalsis. Pyrantel pamoate is most ef­fective on larvae and mature forms of nematodes, that parasitize in the digestive tract (Neoascaris vitulorum, Bunostomum trigonocephalum, Trichostrongylus co­lumbriformis, T. axei, Trichuris skrjabini, T. ovis, Cha­bertia ovina and others).

APPLICATION. The drug is used for cattle, sheep and goats for control of gastrointestinal worms caused by species of trematodes and nematodes sensitive to components of this drug.

Therapeutic and prophylactic treatment of animals is carried out after setting them on the stall maintenance and in spring, before the pasture to pasture, and treat­ment – if there are indications. For duary cattle the preparation should be used after the morning milking. Because the active ingredients of the drug excreted in milk in very small amounts (less than 0.1%), this drug may be used for worm control of  lactating cows.

DOSAGE. Cattle – 1 ml per 10 kg of body weight once with water. In case of  intensive invasion with  paramphistomatosis it is recommended to increase the individual dose  by 25%. Dose for sheep and goats – 1.5 ml per 10 kg of body weight.

CONTRAINDICATIONS. Do not use for emaciated animals.

PRECAUTIONS. After deworming medication cattle meat is not suitable for the food purposes for 14 days, milk – two subsequent milking. Milk received in the first two milking after treatment, is given to unproductive animals. In case of emergency slaughter before the deadline meat is used to feed carnivorous animals or for the production of meat and bone flour.

STORAGE. Dry, dark place at the temperature from 0°C to 25°C.

Expiration date – 2 years from the date of manufac­ture.