Sedazinostar (solution for injections)
Release Type:
Glass vials containing 10, 50 ml, sealed and fixed with an aluminum cap.


Transparent colorless solution.


1 ml of a drug contains active ingredients:

xylazine hydrochloride – 20 mg.

Excipients: methyl parahydroxybenzoate, sodium chloride, water for injection

Pharmacological properties

ATC vet classification code QN05CM92 – Soothing and hypnotic drugs.

Xylazine is a thiazine derivative. Its soothing and analgesic action is the effect of stimulating the alpha2-adrenoreceptors of the central nervous system. Relaxation of skeletal muscles is a consequence of blocking the interneuronal excitation transfer in the spinal cord.

The effect of xylazine begins within 5 -10 minutes, after intravenous – within 3 -5 minutes. Analgesic effect lasts for 10-15 minutes, and sedative – for 0.5-4 hours, depending on the type of animal. The drug acts longer after intramuscular injection.


Sedazinostar is used for cattle, horses, dogs and cats for the purpose of sedation, muscle relaxation, as an analgesic and a means of sedation. The injection of xylazine makes it possible to carry out a survey of excitable animals, the introduction of drugs and perform short-term surgical operations.


Cattle (intramuscular):

0,025 ml of the drug per 10 kg body weight – causes a slight sedative effect, causes slight muscle relaxation and moderate analgesia;

0,05 ml per 10 kg body weight – causes moderate sedation, muscle relaxation and analgesia, sufficient to perform small operations;

0,1 ml of the drug per 10 kg body weight – strong manifestation of all effects, used in combination with local or conductive anesthesia for complex surgical interventions.

If necessary, intravenous injection of the drug dose is reduced by 50%.

Horses: 0,4ml of the drug per 10 kg body weight (intravenously) and 1 ml of the drug per 10 kg body weight (intravenously).

Dogs: (intramuscularly, subcutaneously): at a dose of 0.15 ml / kg body weight.

Cats: (intramuscularly, subcutaneously): at a dose of 0.15 ml / kg body weight.

To prevent impaired cardiac activity, the drug must be injected along with atropine.

When administered intravenously, the drug must be heated to body temperature and injected slowly.


Do not use with arrhythmias of the ventricles of the heart and with shock.

Do not use in case of respiratory system diseases.

Do not use in late pregnancy (the threat of miscarriage), except for childbirth.

Do not use with diabetes (xylazine reduces insulin levels).

Do not use in cases of obstruction of the esophagus in dogs and cats.

Use very carefully with convulsions, acute kidney or liver failure.



  • Xylazine makes it difficult for normal peristalsis of the intestines, so it should be used in horses only for colic, which are not amenable to analgesics; should be avoided in horses with weak motility of the cecum,
  • use caution in horses sensitive to acute diffuse inflammation of the base of the skin of the hoof,
  • animals with symptoms of impaired respiratory system activity or diseases of the respiratory system, life-threatening choking may occur.
  • Use the smallest recommended dose.

Cats and dogs:

  • xylazine blocks the normal intestinal peristalsis, so it should not be used before the x-ray of the stomach and the initial part of the intestine, since the gases that accumulate, do not allow to correctly interpret the results of the study,
  • the dogs of brachiocephalic breeds with symptoms of impaired activity of the respiratory system or with diseases of the respiratory system, life-threatening choking may occur.


  • under the influence of xylazine, the motility of the foreglobe is slowed down, which can cause flatulence, therefore, a few hours before the introduction, it is recommended not to feed or water the animals,
  • after administration of xylazine, the reflexes of ructation, coughing and swallowing are weakened, therefore, during the return to consciousness, the animals must remain in the chest position, it is necessary to carefully monitor them,
  • for cattle it is recommended to administer low and medium doses.

When dosing take into account the individual vulnerability of animals.

To avoid an overdose, you should determine the correct dose, for this you should determine the maximum body weight of the animal.

In case of accidental administration of the drug to yourself, it is necessary to consult a doctor and show the doctor the information sheet or the package.

Drugs that exhibit a neurodepressive effect on the nerve centers (anesthetics, analgesics) enhance the action of xylazine. This causes an increase in the cardiodepressive effect, a weakening of the respiratory functions and a hypotensive action. That is why, the great care must be taken when combining xylazine with opioids.

Xylazine and thiobarbiturates or halothane should not be administered together, as this causes an increase in heart rhythm disturbances.

In view of the danger of uneven functioning of the ventricles of the heart, xylazine cannot be administered along with adrenaline and other agents that excite a sympathetic system, or immediately after their introduction.

Do not use in late pregnancy due to the risk of miscarriage.

Release form

Glass vials containing 10, 50 ml, sealed and fixed with an aluminum cap.


Dry, dark place inaccessible to children at a temperature from + 15 ° to + 25 ° С. Do not freeze.

Expiration date – 2 years.

The contents of the printed package should be used within 28 days, provided that it is stored in a dark place at a temperature between + 2 ° C and + 8 ° C.

For applying in veterinary medicine!