Injection antimicrobials
Peniprok

The white suspension, homogeneous on shaking.

Release Type:
Bottles of transparent brown hydrolytic glass, closed with a rubber stopper under an aluminum run-in 10 and 250 ml of 50,100.
Type of drug:
Injection antimicrobials
Application:
Treatment of cattle, pigs, horses, sheep, goats, dogs and cats omphalitis, arthritis, mastitis, septicemia and secondary infections, and respiratory and urinary tract caused by microorganisms sensitive to penicillin and dihydrostreptomycin.

The white suspension, homogeneous on shaking.

Composition

1 ml of the product contains the active ingredients:

procaine penicillin G 200,000 units;

Dihydrostreptomycin Sulfate 250 mg;

Betamethasone 0.5 mg;

chlorophenylamine maleate 8 mg;

procaine hydrochloride 15 mg;

auxiliaries in 1 ml.

Pharmacological properties

Penicillin G procaine – a beta-lactam antibiotic of the series, which has a wide spectrum of bactericidal activity against gram-positive and gram-negative microorganisms: Corynebacterium pyogenes, Erysipelothrix rhusiopathiae, Listeria spp., Pasteurella haemolytica, Pasteurella multocida, Staphylococcus spp., Streptococcus spp. The mechanism of action of a substance is a violation of the synthesis of peptidoglycan – peptidoglycan cell wall, which leads to the inhibition of synthesis of cell walls of microorganisms, inhibition of growth and reproduction of bacteria.

Dihydrostreptomycin Sulfate – aminoglycoside antibiotic, a bactericidal effect on gram-negative and gram-positive bacteria (Escherichia coli, Salmonella spp., Shigella spp., Yersinia spp., Klebsiella spp., Haemophilus influenzae, Staphylococcus spp., Corynebacterium pyogenes). Substance exhibits bactericidal action due to binding to the 308-subunit of the bacterial ribosome, which subsequently leads to inhibition of protein synthesis.

Chlorophenvlamino maleate acts as a desensitizing, antihistamine. It improves respiratory processes.

Betamethasone – a synthetic corticosteroid, has a pronounced anti-inflammatory action.

Procaine hydrochloride – local anesthetic, which exhibits analgesic and hypotensive effect. For parenteral administration of procaine hydrochloride reduces the production of acetylcholine, reduces the excitability of peripheral than cholinoreactive systems, it contributes to the blocking effects on the autonomic ganglia, reduces spasms of smooth muscles, reduces the excitation of the myocardium and motor areas of the cerebral cortex.

Application

Treatment of cattle, pigs, horses, sheep, goats, dogs and cats omphalitis, arthritis, mastitis, septicemia and secondary infections, and respiratory and urinary tract caused by microorganisms sensitive to penicillin and dihydrostreptomycin.

Dosage

Intramuscularly at a dose of 1-1.5 ml per 10 kg of body weight for 3-4 days, or:

Cattle and horses – 15-25 ml per animal per day;

pig -10-12 ml per animal per day;

dogs and cats – 0.5-2 ml per animal per day.

Contraindications

Hypersensitivity to penicillin and dihydrostreptomycin. Do not use in rabbits, guinea pigs, hamsters and other small herbivores, as well as animals with impaired renal function.

Side effect

Allergic reactions are possible. Sometimes there are cases of transient skin rash, fever, vomiting, tremors, anxiety, and loss of coordination.

There may be small and short-term injection site reactions.

Cautions

Slaughter of animals for meat is permitted in 30 days, the consumption of milk for human consumption – 3 days (6 milkings) after the last treatment. Received by the deadline meat and milk fed or disposed of unproductive animals, according to a doctor of veterinary medicine.

Product form

Bottles of transparent brown hydrolytic glass, closed with a rubber stopper under an aluminum run-in 10 and 250 ml of 50,100.

Storage

Dry, dark, place inaccessible to children at temperature from 5 ° C to 25 ° C.

Shelf life – 2 years from date of manufacture.

After the first selection of the drug from the vial must be used within 28 days when stored in a dark place at a temperature of 2 ° to 8 ° C.

For use in veterinary medicine!