1 ml contains active substance:
fipronil – 80.0 mg;
excipients – up to 1 ml.
Polymer-drip ampoules of 1.0 ml, 4 pieces in cardboard boxes.
DESCRIPTION. A clear, oily liquid from light yellow to red with the smell of a flavoring.
PHARMACOLOGICAL CHARACTERISTICS. АТС vet QP53A, ectoparasitic drugs for local application (QP53AX15, fipronil)
The active substance of the drug – fipronil (Fipronilum)-5-amino-1-[2,6-dichloro-4-(trifluoromethyl)fenil]-4[(trifluoromethyl) sulfinyl]-1Н- pyrazole -3- carbonitrile, derivative of fenilpirazole.
Fipronil acts on the central nervous system of ectoparasites without affecting the central nervous system of animals. The mechanism of action of fipronil in invertebrates is that the drug inhibits the passage of chloride ions in the GABA-dependent chloride channels, disrupting the nervous system. After systematic locking of nervous system with fipronil occurs nervous overexcitement and death of ectoparasites.
After applying the product on the skin fipronil is not absorbed through the skin, and cumulates in the epidermis, sebaceous glands, hair follicles and gradually releases detecting insecticide-acaricide action. Fipronil provides long-term sustained action. After local application the drug is distributed over the body surface of the animal within 24 hours.
APPLICATION. For the treatment of dogs and cats of infestations by: fleas (Ctenocephalus spp.), lice (Linognathus setosus), mallofaga on imaginal and larval stages of development (Trichodectidae), parasitiforme and itch ticks (Dermacentor spp., Ixodes spp., Rhipicephalus spp., Sarcoptes scabiei var. canis). Prevention and treatment of flea allergic dermatitis of dogs and cats.
DOSAGE. For external use only. Apply the product directly to the skin based on weight of the animal.. Before use, cut the tip of the ampoule. The drug is applied on the intact dry skin using polymer ampoule-drip on the place out of the reach of pets to lick off, deploying wool in the area of the spine between the shoulder blades, in the area of the neck, the skin of the inner surface of the ear at the doses given in the table.
When processing large dogs weighing more than 50 kg the dose is increased for 1 ml for every subsequent 10 kg. In case of lesions of itch ticks, lice, mallofaga processing is carried out 2-3 times at intervals of 10-12 days. In order to prevent infestation of animals by ticks it is necessary to periodically make preventive application of drug For optimal control of flea infestation. In the treatment of animals from otoacariasis (ear mange) ear conch and ear canal are previously purified from ear wax, with fluid and scabs, then into each ear instilled 4-6 drops of the drug. For even distribution of the drug ear conch closing with finger and gently massaged along its base, fixing head of the animal for a few minutes to prevent splashing of the drug. Remaining in an ampoule drug put on the animal’s back In case of infestation with ixode ticks the drug (1 drop) is applied directly at ectoparasites in the place of their attachment to the skin (1 drop). If within 30 minutes tick alone does not destroyed, it gently removed with tweezers and destroy.
CONTRAINDICATIONS. Do not use the drug for the sick and exhausted animals, animals during pregnancy and lactation, puppies and kittens up to 10 weeks of age, the dogs weighing up to 1 kg and animals sensitive to the components of the drug.
PRECAUTIONS. Do not let getting the drug inside and on mucous membranes. After processing wash hands with warm water and soap. In case of accidental getting of the drug on the skin or mucous membranes immediately rinse it with running water, with the drug inside – seek immediate medical help. It is not allowed for 48 hours after treatment to bathe and stroke the animals. Avoid licking off the drug from the skin after treatment. In case of overdose atropine sulfate is used in therapeutic doses and symptomatic treatment. Avoid contact with the animal’s eyes. In the case of accidental eye contact immediately and thoroughly flush the eyes with water.
STORAGE. In a dry, dark, well-ventilated area at the temperature from 2°C to 25°C. The drug is stored separately from food and feed. Keep out of reach of children.
SHELF-LIFE – 1 year from the date of manufacture.