Anti-oxidants
Diklox powder

СOMPOSITION

100 g of the drug contains the active sub­stance: diclazuril – 0.2 g

Additional substances: up to 100 g.

PACKAGING

Packages of the polymer film and/or laminated foil, polymer jars with lids (containers) of 50, 200g, 1 kg; bags of 20 kg.

 

DESCRIPTION. Powder from light yellow to yellow color.

PHARMACOLOGICAL CHARACTERISTICS. АТС vet QP51A, drugs against protozoan infections (QP51AJ03, diclazuril)

Diclazuril is a chemical anticoccidial, a benzeneacetonitrile derivative – synthetic compound of the triazinone family. According to the anticoccidial properties of triazinones, diclazuril is active against intracellular development stages of coccidia, namely during schizogony and gametogony. After diclurazil treatment, the first- and second-generation schizonts show extensive degenerative changes which are characterised by the loss of internal structure, the appearance of many intracytoplasmic vacuoles and incomplete merogony. Ultrastructural findings indicate that diclazuril treatment primarily affects the normal differentiation of the respective endogenous stages during parasite development. This leads to complete degeneration of schizonts and gamonts.

The substance acts on all species of poultry eimeria (Eimeria acervulina, E. brunetti, Е. maxima, E. mitis, E. necatrix, E. tenella, E. adenoides, E. gallopavonis, Е. meleagrimitis, E. anseris, E. truncata and etc.), rab­bit eimeria (Е. flavescens, E. intestinalis, E. magna, E. perforans, E. stiedae and other), young cattle eimeria (Е. bovis, E. zuernii, E. ellipsoidalis, E. cylindrica), eimeria of young sheep and goats (Е. crandalis, E. оvinoidalis, E. arloingi, E. intricata, E. faurei), pigs eimeria (Isospora suis, E. suis, E. debliecki, E. scabra, E. perminuta). Diclazuril does not cumulate in organs and tissues of animals and does not caused negative consequences even after increas­ing the recommended dose in 25-50 times.

APPLICATION. Control and treatment  of eimeriosis of cattle (youngsters), sheep (youngsters), goats (young­sters), rabbits (youngsters), pigs (youngsters), poultry (chickens, broilers), waterfowl (young ducks, geese, pheasants, turkeys) caused by different types of eimeria.

DOSAGE. Use orally with feed in doses shown in the table below. The drug is thoroughly mixed with the feed – first with a small part thereof (3-10% of the total), and then the recieved mixture is mixed with the remaining feed.

CONTRAINDICATIONS. Do not use for animals with hypersensitivity to diclazuril. Do not mix or use simultaneously with any other anticoccidial. Do not use for female animals  during pregnancy and lactation, laying-hens and adult poultry.

PRECAUTIONS. Slaughter of poultry for human consumption  is per­mitted in 5 days after the last treatment. The slaughter  of  cattle, sheep, goats, rab­bits, pigs could be performed without restrictions.

STORAGE. Store in dry, dark place, away from children at the temperature from 0°C to 25°C. Do not store together with feed, food and drinks.

SHELF-LIFE – 2 years, after mixing with the feed – 24 hours.